Introduction :
Modern methods of chemotherapy in treating tuber culosis have achieved remarkable
tremendous results in recent years, but the appearance of tubercle bacilli resistant to the
various chemical agents has cast a dark shadow on the treatment of the disease.
Many studies have already been reported on this subject and this requires serious
attention and profound interest in the treatment of the tuberculosis patient.
The author made a comprehnsive study of the resistant tubercule bacilli by stain
method in 702 cases during the period of October 1955 to August 1956 at the T. B.
Center, Taegu Medical College Hospital, to evaluate the percentage of positive stain
cases and positive culture cases as the appearence of resistant strains of tuvercule
bacilli to the chemical agents.
Conclusion :
1) Among the 275 cases of positive culture patients, 161 cases (58.5%)were resistant
to Streptomycin, 49 cases(17.9%) to PAS and 23 cases (8.4%) to INAH.
2) Among the patients who have not been treated with the anti-tuberclosis chemical
agents, 5 cases (7%) were found to be resistant to Streptomycin, and only I case(5%)
was found to be resistant to PAS.
3) The resistance of tuberculose bacilli to the anti-tubenculosis chemical agents was
proportionately stronger as the dosage of the agents employed become greater.
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